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Use of Tricalcium Phosphate in Biomedical Applications

Use of Tricalcium Phosphate in Biomedical Applications

Due to its similarity to the chemical structure of bones and teeth, extensive research has recently been conducted on the use of Tricalcium Phosphate in these fields.

Among its most notable features are its potential for biocompatibility and its non-toxic structure. This allows it to be used safely in the production of biomedical materials.

Calcium phosphate molecules belong to the group of bioactive synthetic materials. The most commonly used compound is Tricalcium Phosphate. Some of the reasons for its preference are its osteoconductive effects (similarities to the chemical phase of bone tissues) and its ability to form excellent chemical and biological bonds with bone tissue, enabling bone tissue growth and development.

Tricalcium phosphate is a chemical in an absorbable form. It exhibits a positive interaction between immature cells, bone cells, and living tissue. Therefore, strong bonding osteogenesis occurs.

Tricalcium phosphate has important properties not only as a calcium source but also as an anti-caking agent within the composition.

How Is It Used?

The first dental implants were described as having tricalcium phosphate content, but later examinations revealed that they were a porous, sintered material composed of a mixture of hydroxyapatite and tricalcium phosphate.

Application Areas of Calcium Phosphates Are As Follows:

  • Repair of Periodontal Defects
  • Augmentation of Alveolar Bone
  • Sinus Lifts
  • Tooth Replacement
  • Repair of Large Defects Caused by Tumors
  • Sealing Agent
  • Cleft Palate
  • Apical Barrier
  • Apexification
  • Vertical Bone Augmentation
  • Implant Coating

It has been used in these areas.

To increase the bioactivity and strength of Calcium Phosphates, they are modified with Titanium Dioxide and used in the production of titanium dioxide alloy implants.

Which Type of Tricalcium Phosphate Should Be Used?

Caution should be exercised when using tricalcium phosphate in biomedical materials. This is because among the many forms of tricalcium phosphate, the Alpha and Beta forms are used as biomaterials in this field.

These chemicals act as osteoconductive materials, thereby enabling bone growth on surfaces, in pores, and in tubes. They are also useful chemicals for inducing hard tissue formation.

Future Use of Calcium Phosphate

It has been determined that the in vivo nucleation and growth of calcium phosphate crystal forms are naturally modified by functional groups within proteins at the mineral level.

The accumulation of bone-like apatite has proven that certain biological properties can be developed for future restorative applications.

How is Tricalcium Phosphate Used in Dental Fillings?

Its degradation and absorption by the body over time make it an ideal material for temporary fillings. It is compatible with dental tissue and provides fluoride, which helps prevent tooth decay. It is also suitable for aesthetic fillings. 

All information here should be used in accordance with the regulations by experts and professionals in the field.
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